Arcoxia Tablet Uses
Arcoxia Tablet Uses
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This information is intended for use by health professionals 1. Qualitative buy Lisinopril quantitative composition Each film-coated tablet contains 30, 60, Arcoxia Tablet Uses, 90 or 120 mg of etoricoxib. Excipients with known effect: Pharmaceutical form Film-coated tablets tablets. Blue-green, apple-shaped biconvex tablets debossed ‘101’ on one side and ‘ACX 30’ on the other side. ARCOXIA is indicated in adults and adolescents 16 years of age and older for the short-term treatment of moderate pain associated with dental surgery. The Arcoxia tablet Uses to prescribe a selective COX-2 inhibitor should be based on an assessment of the individual patient’s Arcoxia tablet Uses risks see sections 4.
The patient’s need for symptomatic relief and response to therapy should be re-evaluated periodically, especially in patients with osteoarthritis see sections 4. Osteoarthritis The recommended dose is 30 mg once daily. In some patients with insufficient relief from symptoms, an increased dose of 60 mg once daily may increase efficacy. In the absence of an increase in therapeutic benefit, other therapeutic options should be considered. Rheumatoid arthritis The recommended dose is 60 mg once daily. In some patients with insufficient relief from symptoms, an increased dose of 90 mg once daily may increase efficacy.
Once the patient is clinically stabilised, down-titration to a 60 mg once daily dose may be buy Cialis days.
Postoperative dental surgery pain The recommended dose is 90 mg once daily, limited to a maximum of 3 days. Doses greater than those recommended for each indication have either not demonstrated additional efficacy or have not been studied. The Arcoxia tablet Uses for OA should not exceed 60 mg daily. The dose for RA and ankylosing spondylitis should not exceed 90 mg daily. The dose for acute gout should not exceed 120 mg daily, limited to a maximum of 8 days treatment, Arcoxia Tablet Uses. The dose for postoperative acute dental Arcoxia tablet Uses pain should not exceed 90 mg daily, limited to a maximum of 3 days. Special populations Elderly patients No dosage adjustment is necessary for elderly patients. Patients with hepatic impairment Regardless of indication, in patients with mild hepatic dysfunction Child-Pugh score 5-6 a dose of 60 mg once daily should not be exceeded.
In patients with moderate hepatic dysfunction Child-Pugh score 7-9, regardless of indication, the dose of 30 mg once daily should not be exceeded.
Clinical experience is limited particularly in patients with moderate hepatic buy Flagyl and caution is advised. Paediatric population Etoricoxib is contra-indicated in Arcoxia tablets Uses and adolescents under 16 years of age see section 4. This should be considered when rapid symptomatic relief is needed. Caution is advised with treatment of patients most at risk of developing a gastrointestinal complication with NSAIDs; the elderly, patients using any other NSAID or acetylsalicylic acid concomitantly or patients with a prior history of gastrointestinal disease, such as ulceration and GI bleeding. There is a further Arcoxia tablet Uses in the risk of gastrointestinal adverse effects gastrointestinal ulceration or other gastrointestinal complications when etoricoxib is taken concomitantly with acetylsalicylic acid even at low doses.
As the cardiovascular risks of etoricoxib may Arcoxia tablet Uses with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used. Patients with significant risk factors for cardiovascular events e. COX-2 selective inhibitors are not a substitute for acetylsalicylic acid for prophylaxis of cardiovascular thrombo-embolic diseases because of their lack of antiplatelet effect.
- If you are about to be started on any new medicine, tell your doctor and pharmacist that you are taking Arcoxia.
- COX-2 selective inhibitors are not a substitute for acetylsalicylic acid for prophylaxis of cardiovascular thrombo-embolic diseases because of their lack of antiplatelet effect.
- Serious hypersensitivity reactions such as anaphylaxis and angioedema have been reported in patients receiving etoricoxib see section 4.
Therefore antiplatelet Arcoxia tablets Uses should not be discontinued see sections above, 4. Renal effects Renal Arcoxia tablets Uses may play a compensatory role in the maintenance pfn.com.mx are those with pre-existing significantly impaired renal function, Arcoxia Tablet Uses, uncompensated Arcoxia tablet Uses failure, or cirrhosis.
Monitoring of renal function in such patients should be considered. Fluid retention, oedema and Arcoxia tablet Uses As with other medicinal products known to inhibit prostaglandin synthesis, fluid retention, oedema and hypertension have been observed in patients taking etoricoxib. For information regarding a dose related response for etoricoxib see section 5. Caution should be exercised in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension and in patients with pre-existing oedema from any other reason. If there is clinical evidence of deterioration in the condition of these patients, appropriate measures including discontinuation of etoricoxib should be taken.
What is Arcoxia?
Etoricoxib may be associated with more frequent and severe hypertension than some Arcoxia tablet Uses NSAIDs buy Indomethacin are detected, etoricoxib should be discontinued. General If during treatment, patients deteriorate in any of the Arcoxia tablet Uses system functions described above, appropriate Arcoxia tablets Uses should be taken and Arcoxia tablet Uses of etoricoxib therapy should be considered.
Medically appropriate supervision should be maintained when using etoricoxib in the elderly and in patients with renal, Arcoxia tablet Uses, or cardiac dysfunction. Caution should be used when initiating treatment with etoricoxib in patients with dehydration. It is advisable to rehydrate Arcoxia tablets Uses prior to starting therapy with etoricoxib.
Serious skin reactions, some of them fatal, including exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported very rarely in association with the use of NSAIDs and some selective COX-2 inhibitors during post-marketing surveillance see section 4. Patients appear to be at highest risk for these reactions early in the course of therapy with the onset of the reaction occurring in the majority of cases within the first month of treatment.
Serious hypersensitivity orangeconcept.vn skin rash, mucosal lesions, or any other sign of hypersensitivity, Arcoxia Tablet Uses.
Etoricoxib may mask fever and other signs of inflammation. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. Therefore, patients receiving oral anticoagulants should be closely monitored for their Arcoxia tablet Uses time INR, particularly in the first few days when therapy with etoricoxib is initiated or the dose of etoricoxib is changed see section 4. In some patients with compromised renal function e. These interactions should be considered in patients taking etoricoxib concomitantly with ACE inhibitors or angiotensin II antagonists.
Arcoxia 30 60 90 120mg film-coated tablets
Patients should be adequately hydrated and consideration should be given to monitoring of renal function after initiation of concomitant therapy, and periodically thereafter. In a study in healthy subjects, at steady state, Arcoxia Tablet Uses, etoricoxib 120 mg once daily had no effect on the anti-platelet activity of acetylsalicylic Arcoxia tablet Uses 81 mg once daily, Arcoxia Tablet Uses. Etoricoxib can be used concomitantly with acetylsalicylic acid at buy Vibramycin when the NSAID is withdrawn.
Etoricoxib at 60 and 90 mg had no effect on methotrexate plasma concentrations or renal clearance. Buy Omnicef 300 mg online usa given concomitantly Arcoxia tablet Uses an oral contraceptive containing 35 micrograms ethinyl estradiol EE and 0. This increase in EE concentration should be considered when selecting an oral contraceptive for use with etoricoxib. An increase in EE exposure can increase the incidence of adverse events associated with oral contraceptives e.
The effect of the recommended chronic Arcoxia tablets Uses of etoricoxib 30, 60, and 90 mg has not been studied. These increases in estrogenic concentration should be taken into consideration when selecting post-menopausal hormone therapy for use with etoricoxib because the increase in oestrogen exposure might increase the risk of adverse events associated with HRT. This increase is not generally important for most patients. CYP3A4 appears to contribute to the Arcoxia tablet Uses of etoricoxib in vivo. While this information may suggest an increase in dose, doses of etoricoxib greater than those listed for each Arcoxia tablet Uses have not been studied in Arcoxia tablet Uses with rifampicin and are therefore not recommended see section 4.
Antacids do not affect the pharmacokinetics of etoricoxib to a clinically relevant extent. Studies in animals have shown reproductive Arcoxia tablet Uses see section 5. The potential for human risk in pregnancy is unknown. Etoricoxib, as with other medicinal products inhibiting prostaglandin Arcoxia tablet Uses, may cause uterine inertia and premature closure of the ductus arteriosus during the last trimester. Etoricoxib is contraindicated in pregnancy see section 4. If a woman becomes pregnant during treatment, etoricoxib must be discontinued. Breastfeeding It is not known whether etoricoxib is excreted in human milk. Etoricoxib is excreted in the milk of lactating rats. Women who use etoricoxib must not breast feed see sections 4.
In clinical studies, Arcoxia Tablet Uses, the Arcoxia tablet Uses effects profile was similar in patients with OA or RA treated with etoricoxib for one year or longer. In a clinical study for acute gouty arthritis, patients were treated with etoricoxib 120 mg orangeconcept.vn daily for eight days. The adverse experience profile in this study was generally similar to that reported in the combined OA, RA, and chronic low back pain studies. In a cardiovascular safety outcomes programme of pooled data from three active comparator controlled Arcoxia tablets Uses, 17, 412 patients with OA or RA were treated with etoricoxib 60 mg or 90 mg for a mean duration of approximately 18 months.
The safety data and details from this programme are presented in section 5. In clinical studies for Arcoxia tablet Uses postoperative dental pain following surgery including 614 patients treated with etoricoxib 90 mg or 120 mg, the adverse experience profile in these studies was generally similar to that reported in the combined OA, RA, and chronic low back pain studies.
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